The Qur'ān and the Bible both mention the "Word of God" as Jesus, the Messenger of God, and His Word committed to Mary. Muslim commentators have debated the meaning of this term, with some suggesting it is the good news given to Mary by God, others stating it was created by God using the word "Be" and the command of God, and others referring to other prophets who came into being by "good news."

The Qur'ān explains that Allah created the world and everything in it by saying the word "Be." Jesus, in God's sight, is like Adam's likeness, created from dust. However, the "Word of God" cannot refer to any creation created by the word "Be." The whole world, including Adam, is created by the word "Be," and Adam, created without a human seed, should also be called the "Word of God."

The Bible describes the "Word of God" as eternal, being with God and being God Himself. Jesus, the crucified Son of God, is depicted as the Word, and the Old Testament concept of the deity of the Messiah is confirmed. The Word is made flesh and dwelt among us, and the revelation about the second coming of Christ is revealed in Revelation. Jesus uses God's name, YHWH, for Himself and accepts worship as God, fulfilling Old Testament prophecy.

The "Word of God" is how God brought creation into existence, and Jesus Christ is the embodiment of this word. The Eternal Word, the Eternal Hope, reconciles God and His creation, restoring the relationship since the Fall. Jesus Christ died on our behalf to bear the punishment for our sins, providing forgiveness, becoming a new creation, and inheriting eternal life. By believing in Jesus Christ, we become a new creation and receive eternal life, with eternal consequences for our decisions.